CATH Domain 2pmwB02

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.120	Jelly Rolls
	2.60.120.690	Proprotein convertase subtilisin/kexin type 9

Domain Context

CATH Clusters

Superfamily	Proprotein convertase subtilisin/kexin type 9
Functional Family	Proprotein convertase subtilisin/kexin type 9

Enzyme Information

3.4.21.-

Serine endopeptidases.

based on mapping to UniProt Q8NBP7

UniProtKB Entries (1)

PCSK9_HUMAN

Homo sapiens

Proprotein convertase subtilisin/kexin type 9

PDB Structure

PDB	2PMW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Crystal Structure of PCSK9: A Regulator of Plasma LDL-Cholesterol. Piper, D.E., Jackson, S., Liu, Q., Romanow, W.G., Shetterly, S., Thibault, S.T., Shan, B., Walker, N.P. Structure