CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.70 | Cathepsin D, subunit A; domain 1 |
|
2.40.70.10 | Acid Proteases |
Domain Context
CATH Clusters
| Superfamily | Acid Proteases |
| Functional Family | Gag-Pol polyprotein |
Enzyme Information
UniProtKB Entries (1)
| Q9J2P7 |
Q9J2P7_9HIV1
Human immunodeficiency virus 1
Protease
|
PDB Structure
| PDB | 2PK5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Compensating enthalpic and entropic changes hinder binding affinity optimization.
Chem.Biol.Drug Des.
|