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CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family

Enzyme Information

2.1.1.72
Site-specific DNA-methyltransferase (adenine-specific).
based on mapping to UniProt Q89Z59
S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N-6-methyladenine in DNA.
-!- This is a large group of enzymes, most of which form so-called 'restriction-modification systems', with nucleases that possess similar site specificity (the nucleases are listed as either EC 3.1.21.3, EC 3.1.21.4 and EC 3.1.21.5). -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/

UniProtKB Entries (1)

Q89Z59
T1M_BACTN
Bacteroides thetaiotaomicron VPI-5482
Probable type I restriction enzyme BthVORF4518P M protein

PDB Structure

PDB 2OKC
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of Type I restriction enzyme StySJI M protein (NP_813429.1) from Bacteroides thetaiotaomicron VPI-5482 at 2.20 A resolution
Joint Center for Structural Genomics (JCSG)
To be Published
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