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1 keywords

CATH Domain 2od2A02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.1600 SIR2/SIRT2 'Small Domain'
Homologous Superfamily 3.30.1600.10 SIR2/SIRT2 'Small Domain'

Domain Context

CATH Clusters

Superfamily SIR2/SIRT2 'Small Domain'
Functional Family NAD-dependent deacetylase sirtuin-3, mitochondrial

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt P53686

UniProtKB Entries (1)

P53686
HST2_YEAST
Saccharomyces cerevisiae S288C
NAD-dependent protein deacetylase HST2

PDB Structure

PDB 2OD2
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes.
Sanders, B.D., Zhao, K., Slama, J.T., Marmorstein, R.
Mol.Cell
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