CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Deoxycytidine kinase

Enzyme Information

2.7.1.113
Deoxyguanosine kinase.
based on mapping to UniProt Q16854
ATP + deoxyguanosine = ADP + dGMP.
-!- Deoxyinosine can also act as acceptor.

UniProtKB Entries (1)

Q16854
DGUOK_HUMAN
Homo sapiens
Deoxyguanosine kinase, mitochondrial

PDB Structure

PDB 2OCP
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural Basis for Substrate Specificities of Cellular Deoxyribonucleoside Kinases.
Johansson, K., Ramaswamy, S., Ljungkrantz, C., Knecht, W., Piskur, J., Munch-Petersen, B., Eriksson, S., Eklund, H.
Nat.Struct.Biol.