CATH Domain 2oatC02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.640	Aspartate Aminotransferase; domain 2
	3.40.640.10	Type I PLP-dependent aspartate aminotransferase-like (Major domain)

Domain Context

CATH Clusters

Superfamily	Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family	Ornithine aminotransferase

Enzyme Information

2.6.1.13

Ornithine aminotransferase.

based on mapping to UniProt P04181

L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.

UniProtKB Entries (1)

OAT_HUMAN

Homo sapiens

Ornithine aminotransferase, mitochondrial

PDB Structure

PDB	2OAT
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine. Storici, P., Capitani, G., Muller, R., Schirmer, T., Jansonius, J.N. J.Mol.Biol.