CATH Domain 2o7nA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.410	von Willebrand factor, type A domain

Domain Context

CATH Clusters

Superfamily	von Willebrand factor, type A domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

ITAL_HUMAN

Homo sapiens

Integrin alpha-L

PDB Structure

PDB	2O7N
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Design of LFA-1 antagonists based on a 2,3-dihydro-1H-pyrrolizin-5(7aH)-one scaffold. Dodd, D.S., Sheriff, S., Chang, C.J., Stetsko, D.K., Phillips, L.M., Zhang, Y., Launay, M., Potin, D., Vaccaro, W., Poss, M.A., McKinnon, M., Barrish, J.C., Suchard, S.J., Murali Dhar, T.G. Bioorg.Med.Chem.Lett.