CATH Classification

Domain Context

CATH Clusters

Superfamily Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Functional Family 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase

Enzyme Information

4.1.1.97
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase.
based on mapping to UniProt A1L259
5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate = (S)- allantoin + CO(2).
-!- This enzyme is part of the pathway from urate to (S)-allantoin, which is present in bacteria, plants and animals (but not in humans). -!- Formerly EC 4.1.1.n1.

UniProtKB Entries (1)

A1L259
URAD_DANRE
Danio rerio
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase

PDB Structure

PDB 2O70
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation.
Cendron, L., Berni, R., Folli, C., Ramazzina, I., Percudani, R., Zanotti, G.
J.Biol.Chem.