CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Serine/threonine-protein kinase pim-1

Enzyme Information
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P11309
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC and EC

UniProtKB Entries (1)

Homo sapiens
Serine/threonine-protein kinase pim-1

PDB Structure

PDB 2O65
External Links
Organism Escherichia
Primary Citation
Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase.
Holder, S., Zemskova, M., Zhang, C., Tabrizizad, M., Bremer, R., Neidigh, J.W., Lilly, M.B.
Mol.Cancer Ther.