CATH Classification

Domain Context

CATH Clusters

Superfamily Rieske [2Fe-2S] iron-sulphur domain
Functional Family Cytochrome b-c1 complex subunit Rieske, mitochondrial

Enzyme Information
Quinol--cytochrome-c reductase.
based on mapping to UniProt Q02762
Quinol + 2 ferricytochrome c(Side 2) = quinone + 2 ferrocytochrome c(Side 2) + 2 H(+)(Side 2).
-!- The enzyme, often referred to as the cytochrome bc1 complex or complex III, is the third complex in the electron transport chain. -!- It is present in the mitochondria of all aerobic eukaryotes and in the inner membranes of most bacteria. -!- The mammalian enzyme contains cytochromes b-562, b-566 and c(1), and a 2-iron ferredoxin. -!- Depending on the organism and physiological conditions, the enzyme extrudes either two or four protons from the cytoplasmic to the non- cytoplasmic compartment (cf. EC -!- Formerly EC

UniProtKB Entries (1)

Rhodobacter sphaeroides
Ubiquinol-cytochrome c reductase iron-sulfur subunit

PDB Structure

External Links
Organism Escherichia
Primary Citation
Atomic resolution structures of rieske iron-sulfur protein: role of hydrogen bonds in tuning the redox potential of iron-sulfur clusters.
Kolling, D.J., Brunzelle, J.S., Lhee, S., Crofts, A.R., Nair, S.K.