CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.20 | Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 |
|
3.60.20.20 | Inosine monophosphate cyclohydrolase-like |
Domain Context
CATH Clusters
| Superfamily | Inosine monophosphate cyclohydrolase-like |
| Functional Family |
Enzyme Information
| 3.5.4.10 |
IMP cyclohydrolase.
based on mapping to UniProt O27099
IMP + H(2)O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.
|
UniProtKB Entries (1)
| O27099 |
PURO_METTH
Methanothermobacter thermautotrophicus str. Delta H
IMP cyclohydrolase
|
PDB Structure
| PDB | 2NTL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
A novel function for the N-terminal nucleophile hydrolase fold demonstrated by the structure of an archaeal inosine monophosphate cyclohydrolase.
Biochemistry
|
