CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.120 | Jelly Rolls |
|
2.60.120.200 |
Domain Context
CATH Clusters
| Superfamily | 2.60.120.200 |
| Functional Family | Botulinum neurotoxin type A |
Enzyme Information
| 3.4.24.69 |
Bontoxilysin.
based on mapping to UniProt P10844
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.
|
UniProtKB Entries (2)
| P29101 |
SYT2_RAT
Rattus norvegicus
Synaptotagmin-2
|
| P10844 |
BXB_CLOBO
Clostridium botulinum
Botulinum neurotoxin type B
|
PDB Structure
| PDB | 2NM1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity.
Nature
|