CATH Domain 2lspB00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Bromodomain-containing protein 2

Enzyme Information

UniProtKB Entries (1)

TF65_HUMAN

Homo sapiens

Transcription factor p65

PDB Structure

PDB	2LSP
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Down-regulation of NF-kappa B transcriptional activity in HIV-associated kidney disease by BRD4 inhibition. Zhang, G., Liu, R., Zhong, Y., Plotnikov, A.N., Zhang, W., Zeng, L., Rusinova, E., Gerona-Nevarro, G., Moshkina, N., Joshua, J., Chuang, P.Y., Ohlmeyer, M., He, J.C., Zhou, M.M. J.Biol.Chem.