×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

1 keywords

CATH Domain 2l8dA00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.30 Roll
Topology 2.30.30 SH3 type barrels.
Homologous Superfamily 2.30.30.140  

Domain Context

CATH Clusters

Superfamily 2.30.30.140
Functional Family Lamin B receptor

Enzyme Information

1.3.1.70
Delta(14)-sterol reductase.
based on mapping to UniProt P23913
4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NADP(+) = 4,4- dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol + NADPH.
-!- Acts on a range of steroids with a 14(15)-double bond.

UniProtKB Entries (1)

P23913
LBR_CHICK
Gallus gallus
Delta(14)-sterol reductase

PDB Structure

PDB 2L8D
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution structure and molecular interactions of lamin B receptor tudor domain.
Liokatis, S., Edlich, C., Soupsana, K., Giannios, I., Panagiotidou, P., Tripsianes, K., Sattler, M., Georgatos, S.D., Politou, A.S.
J.Biol.Chem.
CATH-Gene3D is a Global Biodata Core Resource Learn more...