CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.1020 | CREB-binding Protein; Chain A |
|
1.20.1020.10 | TAZ domain |
Domain Context
CATH Clusters
| Superfamily | TAZ domain |
| Functional Family | E1A binding protein p300 |
Enzyme Information
| 2.3.1.48 |
Histone acetyltransferase.
based on mapping to UniProt P45481
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
|
UniProtKB Entries (2)
| P45481 |
CBP_MOUSE
Mus musculus
CREB-binding protein
|
| P52630 |
STAT2_HUMAN
Homo sapiens
Signal transducer and activator of transcription 2
|
PDB Structure
| PDB | 2KA4 |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains
Embo J.
|
