CATH Domain 2jtcA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.70	Cathepsin B; Chain A
	3.90.70.50	Streptopain (SpeB)

Domain Context

CATH Clusters

Superfamily	Peptidase C10, streptopain
Functional Family

Enzyme Information

3.4.22.10

Streptopain.

based on mapping to UniProt P0C0J1

Preferential cleavage with hydrophobic residues at P2, P1 and P1'.

-!- From the bacterium, group A Streptococcus. -!- Formed from the proenzyme by limited proteolysis. -!- Belongs to peptidase family C10. -!- Formerly EC 3.4.4.18.

UniProtKB Entries (1)

P0C0J1

SPEB_STRP1

Streptococcus pyogenes serotype M1

Streptopain

PDB Structure

PDB	2JTC
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Solution structure and backbone dynamics of streptopain: insight into diverse substrate specificity. Wang, C.C., Houng, H.C., Chen, C.L., Wang, P.J., Kuo, C.F., Lin, Y.S., Wu, J.J., Lin, M.T., Liu, C.C., Huang, W., Chuang, W.J. J.Biol.Chem.