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1 keywords

CATH Domain 2jolA01

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.4120 SopE-like GEF fold
Homologous Superfamily 1.10.4120.10 SopE-like, GEF domain

Domain Context

CATH Clusters

Superfamily SopE-like, GEF domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q63K41
BOPE_BURPS
Burkholderia pseudomallei K96243
Guanine nucleotide exchange factor BopE

PDB Structure

PDB 2JOL
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
The guanine-nucleotide-exchange factor BopE from Burkholderia pseudomallei adopts a compact version of the Salmonella SopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42
Upadhyay, A., Wu, H.L., Williams, C., Field, T., Galyov, E.E., van den Elsen, J.M., Bagby, S.
Biochem.J.
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