CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.1100
Functional Family Cystathionine beta-synthase

Enzyme Information

2.5.1.47
Cysteine synthase.
based on mapping to UniProt P29848
O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.
-!- Some alkyl thiols, cyanide, pyrazole and some other heterocyclic compounds can act as acceptors. -!- Not identical with EC 2.5.1.51, EC 2.5.1.52 and EC 2.5.1.53. -!- Formerly EC 4.2.99.8.

UniProtKB Entries (1)

P29848
CYSM_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Cysteine synthase B

PDB Structure

PDB 2JC3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure, Mechanism, and Conformational Dynamics of O-Acetylserine Sulfhydrylase from Salmonella Typhimurium: Comparison of a and B Isozymes.
Chattopadhyay, A., Meier, M., Ivaninskii, S., Burkhard, P., Speroni, F., Campanini, B., Bettati, S., Mozzarelli, A., Rabeh, W.M., Li, L., Cook, P.F.
Biochemistry