CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.462 | Vanillyl-alcohol Oxidase; Chain A, domain 3 |
|
3.40.462.20 |
Domain Context
CATH Clusters
| Superfamily | 3.40.462.20 |
| Functional Family |
Enzyme Information
| 1.3.3.14 |
Aclacinomycin-A oxidase.
based on mapping to UniProt Q0PCD7
Aclacinomycin A + O(2) = aclacinomycin Y + H(2)O(2).
-!- This bifunctional enzyme is a secreted flavin-dependent enzyme that is involved in the modification of the terminal sugar residues in the biosynthesis of aclacinomycins. -!- The enzyme utilizes the same active site to catalyze the oxidation of the rhodinose moiety of aclacinomycin N to the cinerulose A moiety of aclacinomycin A (cf. EC 1.1.3.45) and the oxidation of the latter to the L-aculose moiety of aclacinomycin Y.
|
| 1.1.3.45 |
Aclacinomycin-N oxidase.
based on mapping to UniProt Q0PCD7
Aclacinomycin N + O(2) = aclacinomycin A + H(2)O(2).
-!- This bifunctional enzyme is a secreted flavin-dependent enzyme that is involved in the modification of the terminal sugar residues in the biosynthesis of aclacinomycins. -!- The enzyme utilizes the same active site to catalyze the oxidation of the rhodinose moiety of aclacinomycin N to the cinerulose A moiety of aclacinomycin A and the oxidation of the latter to the L-aculose moiety of aclacinomycin Y (cf. EC 1.3.3.14).
|
UniProtKB Entries (1)
| Q0PCD7 |
AKNOX_STRGJ
Streptomyces galilaeus
Aclacinomycin-N/aclacinomycin-A oxidase
|
PDB Structure
| PDB | 2IPI |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure determination by multiwavelength anomalous diffraction of aclacinomycin oxidoreductase: indications of multidomain pseudomerohedral twinning.
Acta Crystallogr.,Sect.D
|
