CATH Domain 2imaB01

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.1240	Zincin-like
	3.90.1240.10	Metalloproteases ("zincins"), catalytic domain like

Domain Context

CATH Clusters

Superfamily	Metalloproteases ("zincins"), catalytic domain like
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q84GJ4_CLOBO

Clostridium botulinum

Neurotoxin type A light chain

PDB Structure

PDB	2IMA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structures of Clostridium botulinum Neurotoxin Serotype A Light Chain Complexed with Small-Molecule Inhibitors Highlight Active-Site Flexibility. Silvaggi, N.R., Boldt, G.E., Hixon, M.S., Kennedy, J.P., Tzipori, S., Janda, K.D., Allen, K.N. Chem.Biol.