CATH Domain 2i6aC01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1190	UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase
	3.40.1190.20	Ribokinase

Domain Context

CATH Clusters

Superfamily	3.40.1190.20
Functional Family	Adenosine kinase

Enzyme Information

2.7.1.20

Adenosine kinase.

based on mapping to UniProt P55263

ATP + adenosine = ADP + AMP.

-!- 2-aminoadenosine can also act as acceptor.

UniProtKB Entries (1)

ADK_HUMAN

Homo sapiens

Adenosine kinase

PDB Structure

PDB	2I6A
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structures of human adenosine kinase inhibitor complexes reveal two distinct binding modes. Muchmore, S.W., Smith, R.A., Stewart, A.O., Cowart, M.D., Gomtsyan, A., Matulenko, M.A., Yu, H., Severin, J.M., Bhagwat, S.S., Lee, C.H., Kowaluk, E.A., Jarvis, M.F., Jakob, C.L. J.Med.Chem.