CATH Classification

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (1)

O38731
O38731_9HIV1
Human immunodeficiency virus 1
Protease

PDB Structure

PDB 2I0D
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Discovery of HIV-1 Protease Inhibitors with Picomolar Affinities Incorporating N-Aryl-oxazolidinone-5-carboxamides as Novel P2 Ligands.
Ali, A., Reddy, G.S., Cao, H., Anjum, S.G., Nalam, M.N., Schiffer, C.A., Rana, T.M.
J.Med.Chem.