CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10940 |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.10940 |
| Functional Family | L-arabinose isomerase |
Enzyme Information
| 5.3.1.4 |
L-arabinose isomerase.
based on mapping to UniProt P08202
L-arabinose = L-ribulose.
-!- The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism. -!- The enzyme can also convert D-galactose to D-tagatose with lower efficiency.
|
UniProtKB Entries (1)
| P08202 |
ARAA_ECOLI
Escherichia coli K-12
L-arabinose isomerase
|
PDB Structure
| PDB | 2HXG |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure of Mn2+-bound Escherichia coli L-arabinose Isomerase (ECAI) and Implications in Protein Catalytic Mechanism and Thermo-Stability.
J.Young.Investig.
|
