×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (1)

Q7SSI0
Q7SSI0_9HIV1
Human immunodeficiency virus 1
Protease

PDB Structure

PDB 2HS2
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Ultra-high Resolution Crystal Structure of HIV-1 Protease Mutant Reveals Two Binding Sites for Clinical Inhibitor TMC114.
Kovalevsky, A.Y., Liu, F., Leshchenko, S., Ghosh, A.K., Louis, J.M., Harrison, R.W., Weber, I.T.
J.Mol.Biol.
CATH-Gene3D is a Global Biodata Core Resource Learn more...