CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1220 | TPP-binding domain |
Domain Context
CATH Clusters
| Superfamily | TPP-binding domain |
| Functional Family | NAD-dependent histone deacetylase SIR2 |
Enzyme Information
| 3.5.1.- |
In linear amides.
based on mapping to UniProt P06700
|
UniProtKB Entries (1)
| P06700 |
SIR2_YEAST
Saccharomyces cerevisiae S288C
NAD-dependent histone deacetylase SIR2
|
PDB Structure
| PDB | 2HJH |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Autoregulation of the yeast Sir2 deacetylase by reaction and trapping of a pseudosubstrate motif in the active site
To be Published
|