CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family

Enzyme Information

2.7.6.1
Ribose-phosphate diphosphokinase.
based on mapping to UniProt P60891
ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- dATP can also act as donor.

UniProtKB Entries (1)

P60891
PRPS1_HUMAN
Homo sapiens
Ribose-phosphate pyrophosphokinase 1

PDB Structure

PDB 2H06
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site
Li, S., Lu, Y., Peng, B., Ding, J.
Biochem.J.