CATH Domain 2gt7A03

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.1840	main proteinase (3clpro) structure, domain 3
	1.10.1840.10	main proteinase (3clpro) structure, domain 3

Domain Context

CATH Clusters

Superfamily	main proteinase (3clpro) structure, domain 3
Functional Family	Replicase polyprotein 1a

Enzyme Information

UniProtKB Entries (1)

Q1EFP6_CVHSA

SARS coronavirus BJ162

Orf1a polyprotein

PDB Structure

PDB	2GT7
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal Structures Reveal an Induced-fit Binding of a Substrate-like Aza-peptide Epoxide to SARS Coronavirus Main Peptidase. Lee, T.W., Cherney, M.M., Liu, J., James, K.E., Powers, J.C., Eltis, L.D., James, M.N.G. J.Mol.Biol.