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1 keywords

CATH Domain 2gffB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.70 Alpha-Beta Plaits
Homologous Superfamily 3.30.70.100  

Domain Context

CATH Clusters

Superfamily 3.30.70.100
Functional Family (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase

Enzyme Information

5.3.1.32
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase.
based on mapping to UniProt Q7CG46
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione = 3-hydroxy-5- phosphonooxypentane-2,4-dione.
-!- The enzyme participates in a degradation pathway of the bacterial quorum-sensing autoinducer molecule AI-2.

UniProtKB Entries (1)

Q7CG46
LSRG_YERPE
Yersinia pestis
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase

PDB Structure

PDB 2GFF
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of lsrG from Yersinia Pestis
de Carvalho-Kavanagh, M., Schafer, J., Lekin, T., Toppani, D., Coleman, M., Chain, P., Lao, V., Zemla, A., Motin, V., Garcia, E., Segelke, B.
To be Published
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