CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.270 | Reverse transcriptase/Diguanylate cyclase domain |
Domain Context
CATH Clusters
| Superfamily | 3.30.70.270 |
| Functional Family |
Enzyme Information
UniProtKB Entries (1)
| Q99AU2 |
Q99AU2_9HEPC
Hepatitis C virus subtype 1b
Genome polyprotein
|
PDB Structure
| PDB | 2GC8 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Discovery of Proline Sulfonamides as Potent and Selective Hepatitis C Virus NS5b Polymerase Inhibitors. Evidence for a New NS5b Polymerase Binding Site.
J.Med.Chem.
|