CATH Domain 2g36A02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.240	Tyrosyl-Transfer RNA Synthetase
	1.10.240.10	Tyrosyl-Transfer RNA Synthetase

Domain Context

CATH Clusters

Superfamily	Tyrosyl-Transfer RNA Synthetase
Functional Family	Tryptophan--tRNA ligase

Enzyme Information

6.1.1.2

Tryptophan--tRNA ligase.

based on mapping to UniProt Q9WYW2

ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl- tRNA(Trp).

UniProtKB Entries (1)

SYW_THEMA

Thermotoga maritima MSB8

Tryptophan--tRNA ligase

PDB Structure

PDB	2G36
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster. Han, G.W., Yang, X.L., McMullan, D., Chong, Y.E., Krishna, S.S., Rife, C.L., Weekes, D., Brittain, S.M., Abdubek, P., Ambing, E., Astakhova, T., Axelrod, H.L., Carlton, D., Caruthers, J., Chiu, H.J., Clayton, T., Duan, L., Feuerhelm, J., Grant, J.C., Grzechnik, S.K., Jaroszewski, L., Jin, K.K., Klock, H.E., Knuth, M.W., Kumar, A., Marciano, D., Miller, M.D., Morse, A.T., Nigoghossian, E., Okach, L., Paulsen, J., Reyes, R., van den Bedem, H., White, A., Wolf, G., Xu, Q., Hodgson, K.O., Wooley, J., Deacon, A.M., Godzik, A., Lesley, S.A., Elsliger, M.A., Schimmel, P., Wilson, I.A. Acta Crystallogr.,Sect.F