×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

1 keywords

CATH Domain 2fvmB02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.140 Metal-dependent hydrolases

Domain Context

CATH Clusters

Superfamily Metal-dependent hydrolases
Functional Family

Enzyme Information

3.5.2.2
Dihydropyrimidinase.
based on mapping to UniProt Q9P903
5,6-dihydrouracil + H(2)O = 3-ureidopropanoate.
-!- Also acts on dihydrothymine and hydantoin.

UniProtKB Entries (1)

Q9P903
DPYS_LACK1
Lachancea kluyveri NRRL Y-12651
Dihydropyrimidinase

PDB Structure

PDB 2FVM
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The Crystal Structures of Dihydropyrimidinases Reaffirm the Close Relationship between Cyclic Amidohydrolases and Explain Their Substrate Specificity.
Lohkamp, B., Andersen, B., Piskur, J., Dobritzsch, D.
J.Biol.Chem.
CATH-Gene3D is a Global Biodata Core Resource Learn more...