CATH Classification

Domain Context

CATH Clusters

Superfamily Cupredoxins - blue copper proteins
Functional Family

Enzyme Information
Nitrite reductase (NO-forming).
based on mapping to UniProt P38501
Nitric oxide + H(2)O + ferricytochrome c = nitrite + ferrocytochrome c + 2 H(+).
-!- The reaction is catalyzed by two types of enzymes, found in the perimplasm of denitrifying bacteria. -!- One type comprises proteins containing multiple copper centers, the other a heme protein, cytochrome cd1. -!- Acceptors include c-type cytochromes such as cytochrome c-550 or cytochrome c-551 from Paracoccus denitrificans or Pseudomonas aeruginosa, and small blue copper proteins such as azurin and pseudoazurin. -!- Cytochrome cd1 also has oxidase and hydroxylamine reductase activities. -!- May also catalyze the reaction of EC since this is a well- known activity of cytochrome cd1. -!- Formerly EC, EC and EC

UniProtKB Entries (1)

Alcaligenes faecalis
Copper-containing nitrite reductase

PDB Structure

External Links
Organism Escherichia
Primary Citation
Effect of the methionine ligand on the reorganization energy of the type-1 copper site of nitrite reductase.
Wijma, H.J., MacPherson, I., Farver, O., Tocheva, E.I., Pecht, I., Verbeet, M.P., Murphy, M.E.P., Canters, G.W.