×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily Aldehyde Dehydrogenase; Chain A, domain 2
Functional Family NADP-dependent glyceraldehyde-3-phosphate dehydrogenase

Enzyme Information

1.2.1.9
Glyceraldehyde-3-phosphate dehydrogenase (NADP(+)).
based on mapping to UniProt Q59931
D-glyceraldehyde 3-phosphate + NADP(+) + H(2)O = 3-phospho-D-glycerate + NADPH.

UniProtKB Entries (1)

Q59931
GAPN_STRMU
Streptococcus mutans UA159
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase

PDB Structure

PDB 2ESD
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The first crystal structure of a thioacylenzyme intermediate in the ALDH family: new coenzyme conformation and relevance to catalysis
D'Ambrosio, K., Pailot, A., Talfournier, F., Didierjean, C., Benedetti, E., Aubry, A., Branlant, G., Corbier, C.
Biochemistry
CATH-Gene3D is a Global Biodata Core Resource Learn more...