CATH Classification

Domain Context

CATH Clusters

Superfamily 3.10.450.40
Functional Family

Enzyme Information
Primary-amine oxidase.
based on mapping to UniProt P46881
RCH(2)NH(2) + H(2)O + O(2) = RCHO + NH(3) + H(2)O(2).
-!- A group of enzymes that oxidize primary monoamines but have little or no activity toward diamines, such as histamine, or toward secondary and tertiary amines. -!- They are copper quinoproteins (2,4,5-trihydroxyphenylalanine quinone) and, unlike EC, are sensitive to inhibition by carbonyl-group reagents, such as semicarbazide. -!- In some mammalian tissues the enzyme also functions as a vascular- adhesion protein (VAP-1). -!- Formerly EC

UniProtKB Entries (1)

Arthrobacter globiformis
Phenylethylamine oxidase

PDB Structure

External Links
Organism Escherichia
Primary Citation
Catalytic Regulation Conducted by the Substrate Schiff Base and Conserved Aspartic Acid Residue in Bacterial Copper Amine Oxidase Reaction
Murakawa, T., Okajima, T., Taki, M., Yamamoto, Y., Kuroda, S., Hayashi, H., Tanizawa, K.
To be Published