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1 keywords

CATH Domain 2df3A00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Sialic acid-binding Ig-like lectin 8

Enzyme Information

UniProtKB Entries (1)

Q9Y286
SIGL7_HUMAN
Homo sapiens
Sialic acid-binding Ig-like lectin 7

PDB Structure

PDB 2DF3
External Links
Method X-RAY DIFFRACTION
Organism Cricetulus
Primary Citation
The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor design
Attrill, H., Takazawa, H., Witt, S., Kelm, S., Isecke, R., Brossmer, R., Ando, T., Ishida, H., Kiso, M., Crocker, P.R., van Aalten, D.M.F.
Biochem.J.
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