CATH Classification

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family

Enzyme Information

1.1.1.299
Malate dehydrogenase (NAD(P)(+)).
based on mapping to UniProt Q9YEA1
(S)-malate + NAD(P)(+) = oxaloacetate + NAD(P)H.
-!- This enzyme, which was characterized from the methanogenic archaeon Methanobacterium thermoautotrophicum, catalyzes only the reduction of oxaloacetate, and can use NAD(+) and NADP(+) with similar specific activity. -!- Different from EC 1.1.1.37, EC 1.1.1.82 and EC 1.1.5.4.

UniProtKB Entries (1)

Q9YEA1
MDH_AERPE
Aeropyrum pernix K1
Malate dehydrogenase

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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