CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.10 | Thrombin, subunit H |
|
2.40.10.10 | Trypsin-like serine proteases |
Domain Context
CATH Clusters
| Superfamily | Trypsin-like serine proteases |
| Functional Family | Chymotrypsin-like elastase family member 1 |
Enzyme Information
| 3.4.21.36 |
Pancreatic elastase.
based on mapping to UniProt P00772
Hydrolysis of proteins, including elastin. Preferential cleavage: Ala-|-Xaa.
-!- Formed by activation of proelastase from mammalian pancreas by trypsin. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.7 and EC 3.4.21.11.
|
UniProtKB Entries (2)
| P00772 |
CELA1_PIG
Sus scrofa
Chymotrypsin-like elastase family member 1
|
| P01009 |
A1AT_HUMAN
Homo sapiens
Alpha-1-antitrypsin
|
PDB Structure
| PDB | 2D26 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Active Site Distortion Is Sufficient for Proteinase Inhibition by Serpins: Structure of the covalent complex of alpha 1-proteinase inhibitor with porcine pancreatic elastase
J.Biol.Chem.
|
