CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Estrogen sulfotransferase |
Enzyme Information
| 2.8.2.1 |
Aryl sulfotransferase.
based on mapping to UniProt P50225
3'-phosphoadenylyl sulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate.
-!- A number of aromatic compounds can act as acceptors. -!- Organic hydroxylamines are not substrates (cf. EC 2.8.2.9).
|
UniProtKB Entries (1)
| P50225 |
ST1A1_HUMAN
Homo sapiens
Sulfotransferase 1A1
|
PDB Structure
| PDB | 2D06 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The structure of human SULT1A1 crystallized with estradiol. An insight into active site plasticity and substrate inhibition with multi-ring substrates
J.Biol.Chem.
|
