CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Putative Casein kinase I

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P40233
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P40233
CKI1_SCHPO
Schizosaccharomyces pombe 972h-
Casein kinase I homolog 1

PDB Structure

PDB 2CSN
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for selectivity of the isoquinoline sulfonamide family of protein kinase inhibitors.
Xu, R.M., Carmel, G., Kuret, J., Cheng, X.
Proc.Natl.Acad.Sci.USA