CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.120 | Jelly Rolls |
|
2.60.120.330 | B-lactam Antibiotic, Isopenicillin N Synthase; Chain |
Domain Context
CATH Clusters
| Superfamily | B-lactam Antibiotic, Isopenicillin N Synthase; Chain |
| Functional Family |
Enzyme Information
| 1.21.3.1 |
Isopenicillin-N synthase.
based on mapping to UniProt P05326
N-((5S)-5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine + O(2) = isopenicillin N + 2 H(2)O.
-!- Forms part of the penicillin biosynthesis pathway.
|
UniProtKB Entries (1)
| P05326 |
IPNS_EMENI
Aspergillus nidulans FGSC A4
Isopenicillin N synthase
|
PDB Structure
| PDB | 2BJS |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Terminally Truncated Isopenicillin N Synthase Generates a Dithioester Product: Evidence for a Thioaldehyde Intermediate during Catalysis and a New Mode of Reaction for Non-Heme Iron Oxidases.
Chemistry
|
