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1 keywords

CATH Domain 2b3jC00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.140 Cytidine Deaminase; domain 2
Homologous Superfamily 3.40.140.10 Cytidine Deaminase, domain 2

Domain Context

CATH Clusters

Superfamily Cytidine Deaminase, domain 2
Functional Family tRNA-specific adenosine deaminase

Enzyme Information

3.5.4.33
tRNA(adenine(34)) deaminase.
based on mapping to UniProt Q99W51
Adenine(34) in tRNA + H(2)O = hypoxanthine(34) in tRNA + NH(3).
-!- The enzyme is involved in editing of tRNA.

UniProtKB Entries (1)

Q99W51
TADA_STAAM
Staphylococcus aureus subsp. aureus Mu50
TRNA-specific adenosine deaminase

PDB Structure

PDB 2B3J
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA.
Losey, H.C., Ruthenburg, A.J., Verdine, G.L.
Nat.Struct.Mol.Biol.
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