×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily Laminin
Functional Family Prostaglandin G/H synthase 2

Enzyme Information

1.14.99.1
Prostaglandin-endoperoxide synthase.
based on mapping to UniProt P05979
Arachidonate + AH(2) + 2 O(2) = prostaglandin H(2) + A + H(2)O.
-!- Acts both as a dioxygenase and as a peroxidase.

UniProtKB Entries (1)

P05979
PGH1_SHEEP
Ovis aries
Prostaglandin G/H synthase 1

PDB Structure

PDB 2AYL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
2.0 angstroms structure of prostaglandin H2 synthase-1 reconstituted with a manganese porphyrin cofactor.
Gupta, K., Selinsky, B.S., Loll, P.J.
Acta Crystallogr.,Sect.D
CATH-Gene3D is a Global Biodata Core Resource Learn more...