CATH Domain 2atmA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.70	Aldolase class I

Domain Context

CATH Clusters

Superfamily	Aldolase class I
Functional Family

Enzyme Information

3.2.1.35

Hyaluronoglucosaminidase.

based on mapping to UniProt P49370

Random hydrolysis of (1->4)-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.

-!- Also hydrolyzes 1,4-beta-D-glycosidic linkages between N-acetyl- galactosamine or N-acetylgalactosamine sulfate and glucuronic acid in chondroitin, chondroitin 4- and 6-sulfates, and dermatan. -!- Formerly EC 3.2.1.34.

UniProtKB Entries (1)

P49370

HUGAA_VESVU

Vespula vulgaris

Hyaluronidase A

PDB Structure

PDB	2ATM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structure of recombinant Ves v 2 at 2.0 Angstrom resolution: structural analysis of an allergenic hyaluronidase from wasp venom. Skov, L.K., Seppala, U., Coen, J.J., Crickmore, N., King, T.P., Monsalve, R., Kastrup, J.S., Spangfort, M.D., Gajhede, M. Acta Crystallogr.,Sect.D