CATH Classification

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family Histone-lysine N-methyltransferase

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q9NQR1
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
2.1.1.-
Methyltransferases.
based on mapping to UniProt Q9NQR1

UniProtKB Entries (1)

P62805
H4_HUMAN
Homo sapiens
Histone H4

PDB Structure

PDB 1ZKK
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase
Couture, J.-F., Collazo, E., Brunzelle, J.S., Trievel, R.C.
Genes Dev.