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CATH Classification

Domain Context

CATH Clusters

Superfamily Metalloproteases ("zincins"), catalytic domain like
Functional Family Botulinum neurotoxin type B

Enzyme Information

3.4.24.68
Tentoxilysin.
based on mapping to UniProt P04958
Hydrolysis of 76-Gln-|-Phe-77 bond in synaptobrevin 2.
-!- Belongs to peptidase family M27.

UniProtKB Entries (1)

P04958
TETX_CLOTE
Clostridium tetani E88
Tetanus toxin

PDB Structure

PDB 1Z7H
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
2.3A Crystal structure of tetanus neurotoxin light chain
Breidenbach, M.A., Brunger, A.T.
Biochemistry
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