CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.140 | Metal-dependent hydrolases |
Domain Context
CATH Clusters
| Superfamily | Metal-dependent hydrolases |
| Functional Family | Adenosine deaminase |
Enzyme Information
| 3.5.4.4 |
Adenosine deaminase.
based on mapping to UniProt P56658
Adenosine + H(2)O = inosine + NH(3).
|
UniProtKB Entries (1)
| P56658 |
ADA_BOVIN
Bos taurus
Adenosine deaminase
|
PDB Structure
| PDB | 1WXZ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Rational design of non-nucleoside, potent, and orally bioavailable adenosine deaminase inhibitors: predicting enzyme conformational change and metabolism
J.Med.Chem.
|