CATH Classification

Domain Context

CATH Clusters

Superfamily Electron Transport, Fmn-binding Protein; Chain A
Functional Family

Enzyme Information

1.4.3.5
Pyridoxal 5'-phosphate synthase.
based on mapping to UniProt P0AFI7
(1) Pyridoxamine 5'-phosphate + H(2)O + O(2) = pyridoxal 5'-phosphate + NH(3) + H(2)O(2). (2) Pyridoxine 5'-phosphate + O(2) = pyridoxal 5'-phosphate + H(2)O(2).
-!- In Escherichia coli, the coenzyme pyridoxal 5'-phosphate is synthesized de novo by a pathway that involves EC 1.2.1.72, EC 1.1.1.290, EC 2.6.1.52, EC 1.1.1.262, EC 2.6.99.2 and EC 1.4.3.5.

UniProtKB Entries (1)

P0AFI7
PDXH_ECOLI
Escherichia coli K-12
Pyridoxine/pyridoxamine 5'-phosphate oxidase

PDB Structure

PDB 1WV4
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of Escherichia coli pyridoxine 5'-phosphate oxidase in a tetragonal crystal form: insights into the mechanistic pathway of the enzyme.
Safo, M.K., Musayev, F.N., Schirch, V.
Acta Crystallogr.,Sect.D