CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.120 | 6 Propeller | |
2.120.10 | Neuraminidase | |
2.120.10.10 |
Domain Context
CATH Clusters
Superfamily | 2.120.10.10 |
Functional Family |
Enzyme Information
3.2.1.18 |
Exo-alpha-sialidase.
based on mapping to UniProt Q6XV27
Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
-!- The enzyme does not act on 4-O-acetylated sialic acids. -!- An endo-alpha-sialidase activity is listed as EC 3.2.1.129. -!- See also EC 4.2.2.15.
|
UniProtKB Entries (1)
Q6XV27 |
NRAM_I56A2
Influenza A virus (A/duck/England/1/1956(H11N6))
Neuraminidase
|
PDB Structure
PDB | 1W21 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
The Crystal Structure of Type a Influenza Virus Neuraminidase of the N6 Subtype Reveals the Existence of Two Separate Neu5Ac Binding Sites
To be Published
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