CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.180 | Quinone Oxidoreductase; Chain A, domain 1 |
|
3.90.180.10 | Medium-chain alcohol dehydrogenases, catalytic domain |
Domain Context
CATH Clusters
| Superfamily | Medium-chain alcohol dehydrogenases, catalytic domain |
| Functional Family | Prostaglandin reductase 2 |
Enzyme Information
| 1.3.1.48 |
15-oxoprostaglandin 13-reductase.
based on mapping to UniProt Q8VDQ1
11-alpha-hydroxy-9,15-dioxoprost-5-enoate + NAD(P)(+) = (5Z)-(13E)-11- alpha-hydroxy-9,15-dioxoprosta-5,13-dienoate + NAD(P)H.
-!- Reduces 15-oxoprostaglandins to 13,14-dihydro derivatives. -!- The enzyme from placenta is specific for NAD(+).
|
UniProtKB Entries (1)
| Q8VDQ1 |
PTGR2_MOUSE
Mus musculus
Prostaglandin reductase 2
|
PDB Structure
| PDB | |
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| Method | |
| Organism | |
| Primary Citation |
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