CATH Classification

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family L-lactate dehydrogenase A chain

Enzyme Information

1.1.1.27
L-lactate dehydrogenase.
based on mapping to UniProt Q9W7K5
(S)-lactate + NAD(+) = pyruvate + NADH.
-!- Also oxidizes other (S)-2-hydroxymonocarboxylic acids. -!- NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme.

UniProtKB Entries (1)

Q9W7K5
LDHA_CYPCA
Cyprinus carpio
L-lactate dehydrogenase A chain

PDB Structure

PDB 1V6A
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of L-lactate dehydrogenase from Cyprinus carpio
Watanabe, K., Motoshima, H.
To be Published